Prof. Simonetta Geninatti Crich
University of Torino, Department of Molecular Biotechnology and Health Sciences (Torino, Italy)
+39 011 6706473
Expertise in the field of Molecular Imaging with particular interest for the set up of: 1) Protein based innovative nanotheranostic delivery systems; 2) Efficient MRI cellular labeling procedures for an early diagnosis of the pathology; 3) Visualization of drug delivery processes; 4) Development of boron containing agents for Boron Neutron Capture Therapy functionalized with MRI contrast agents for boron quantification; The nanosized delivery systems used in her research are, for example, liposomes, polylactic and glycolic (PLGA) nanoparticles and natural proteins such us ferritin and Low density Lipoproteins (LDL) that can be loaded with both therapeutic and imaging agents. She has developed pH dependent methods to load metal ions, drugs, imaging agents in the apoferritin cavity. The other important area of her research is the development of Gd and boron containing agents for MRI guided Boron Neutron Capture Therapy for personalized treatment.